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Arizona Cardinals free safety Tyrann Mathieu (32) runs back an interception as San Francisco 49ers running back Carlos Hyde (28) defends during the first half of an NFL football game, Sunday, Sept. 27, 2015, in Glendale, Ariz. (AP Photo/Ross D. Franklin)

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Rick Scuteri
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Arizona Cardinals free safety Tyrann Mathieu (32) runs back an interception as San Francisco 49ers running back Carlos Hyde (28) defends during the first half of an NFL football game, Sunday, Sept. 27, 2015, in Glendale, Ariz. (AP Photo/Ross D. Franklin)